The Journal of Biological Physics and Chemistry

2003

Volume 3, Number 2, pp. 45-48

M. Kurashvili, M. Pruidze, E. Kiskeidze, T. Varazashvili, T. Ananiashvili, G. Khatisashvili and M. Gordeziani 

Durmishidze Institute of Biochemistry and Biotechnology, Georgian Academy of Sciences,  David Agmasheneblis Kheivani 10 km, 350059 Tbilisi, Georgia

Influence of different factors on nitrobenzene oxidation in the plant cell

Nitrobenzene oxidation has been studied in soybean (Glycine max) and maize (Zea mays) root subcellular fractions, where the NADPH-dependent monoöxygenase mechanism is of great importance. The influence of different factors on nitrobenzene oxidation has been investigated. It was demonstrated that as the plants age the monoöxygenase mechanism of nitrobenzene oxidation was changed with peroxidase. The peroxidase and phenol oxidase systems were activated due to the action of light against a background of monoöxygenase reduction. In plants infected with Fusarium, the phenol oxidase system was inhibited and the activities of the two other systems were sharply increased. Low-temperature stress significantly blocked activities of all three oxidative systems. N,N-dimethylaniline enhanced NADPH-dependent nitrobenzene hydroxylation and 3,4-benzpyrene (benzopyrene) activated H2O2-dependent nitrobenzene oxidation. Nitrobenzene as an inducer enhanced nitrobenzene oxidation via both the monoöxygenase and peroxidase mechanisms.

Keywords:
cytochrome P450-containing monooxygenase; peroxidase; phenol oxidase; xenobiotic


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